72 major genetic risk factors for breast cancer identified in new study

Breast cancer

Shirts are $20 each and proceeds will benefit local breast cancer awareness and support groups.

The American Cancer Society estimated nearly 500 men will die from breast cancer in 2017. The inherited component of breast cancer risk is due to a combination of rare variants in genes such as BRCA1 and BRCA2 that confer a high risk of the disease, and many commoner genetic variants that each confer only a small risk.

"(Saturday's) event was a moving example of passion in action", said Kathryn Tucker, American Cancer Society Community Development Manager, in a news release announcing the figures.

The National Cancer Institute says only 1% of males can get breast cancer, one of these men is Cecil Herrin.

Pinpointing specific genes is hard, but the OncoArray scientists were able to make predictions about many target genes - a first step towards designing new treatments.

Mutations in these genes prevent them from repairing changes in other sections of DNA in breast tissue, raising the risk of further mutation.




The newly identified risk regions almost double the number that are already known, thereby bringing the number of known common variants associated with breast cancer to around 180.

McCain said women between the ages of 40 and 49 are at a higher risk of developing breast cancer, which is why they shouldn't delay their mammogram. Now, we have access to more accurate mammograms, such as the Genius 3D Mammography exam, that detects more invasive cancers, reduces false positives and is clinically proven as superior for women of all ages - even those with dense breasts compared to traditional 2D mammography.

The findings are published today in the journals Nature and Nature Genetics.

Others, known as oestrogen-receptor negative, are not affected by the hormone and are more hard to treat. Fortunately, today's breast cancer screening technology has advanced tremendously since 1985, and since I was diagnosed with cancer more than 11 years ago. He was diagnosed with breast cancer in 2012 and it changed his life. Another prospective study has shown the greatest reduction in breast cancer risk for women who reported walking/hiking for 10 hours per week.

"Some of the variations are protective, others increase the risk". QIMR Berghofer senior researcher Jonathan Beesley said researchers now knew much more about the genetic mechanisms that might cause breast cancer.

Professor Jacques Simard, from Laval University in Quebec city, Canada, another member of the worldwide team, said: 'Using data from genomic studies, combined with information on other known risk factors, will allow better breast cancer risk assessment, therefore helping to identify a small but meaningful proportion of women at high risk of breast cancer.

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